You might be experiencing a sever infection or a system corruption ( the files that dont run in safe mode but real mode might have been corrupted such as drivers ) but these are all assumptions right now. Please get into safe mode with networking. Click on greyknights link below and follow the instructions for a malware clean-up. Get a hjt log and post it under hjt log help forum. Lets see what happens. Let us know.
regards.
regards.