Well, looking at Epson's website, this thing is for Mac OS 8.6-10.1.3, but they do have drivers for it for up to OS X 10.6. There will be no Epson window come up, all the options will be somewhere in the standard print window. Also, not all programs support all the features of the printer. When you select print, the sheet should roll out from the top of the window. In the Printer pull down, your default printer is listed. If it is not the R800, then click on the printer listed and select the R800 from the list. Now, if all you see is a printer selection and presets selection, then the window is set to default options. You need to click on the square button with a triangle in it that is to the right of the printer selection. Now it will point the triangle up and you will get the full print window, which includes a preview. Now in the expanded print window, look for a pull down with the program's name on it, this is the option section. Click on it and there will be a list of things. Go through those and make any changes you want, like gamma, page order, paper type, and the like.