I would try Go The Power's suggestion and if that doesn't work for you, you could be opening Internet Explorer with a bad desktop shortcut.
If this is the case, you should be able to fix the problem by right clicking on your Internet Explorer icon --> properties
On the Shortcut tab where it says Target: make sure that "C:\Program Files\Internet Explorer\iexplore.exe" is entered.
Click apply and then try opening Internet Explorer again from that icon.
Does that solve your issue?
IE Outreach Team