I assume you're talking about running a Windows program on Mac OS X. Short answer is no. Programs in their machine code state are very dependent on OS specific libraries, etc.
Long answer: maybe. If the machine running Mac OS X is an Intel based Mac, then you could look into programs like Crossover, Parallels and Bootcamp. I haven't been able to experiment with these products yet due to my lack of an Intel based Mac.
Bootcamp lets you dual boot your computer so you can have Mac OS X on one part of the hard drive and Windows on the other. The downside for this is you have to switch between the operating systems. However, it is a good option if you are ok with rebooting the computer to use Windows and Win apps.
Parallels runs what is called a virtual machine. A virtual machine basically is like having a Windows machine running inside your Mac OS X machine. A downside of this that is shared with Bootcamp is that you need a fully licensed version of Windows to install on you machine. I think you can also run Linux inside a virtual machine with Parallels.
Crossover is a program that offers the Windows programs what they need to run without having a copy of Windows. Not needing a copy of Windows is a big upside to this program. I haven't researched this one specifically, but the usual downside is that it doesn't support all programs as well as running Windows with either Parallels or Bootcamp.
Long answer: maybe. If the machine running Mac OS X is an Intel based Mac, then you could look into programs like Crossover, Parallels and Bootcamp. I haven't been able to experiment with these products yet due to my lack of an Intel based Mac.
Bootcamp lets you dual boot your computer so you can have Mac OS X on one part of the hard drive and Windows on the other. The downside for this is you have to switch between the operating systems. However, it is a good option if you are ok with rebooting the computer to use Windows and Win apps.
Parallels runs what is called a virtual machine. A virtual machine basically is like having a Windows machine running inside your Mac OS X machine. A downside of this that is shared with Bootcamp is that you need a fully licensed version of Windows to install on you machine. I think you can also run Linux inside a virtual machine with Parallels.
Crossover is a program that offers the Windows programs what they need to run without having a copy of Windows. Not needing a copy of Windows is a big upside to this program. I haven't researched this one specifically, but the usual downside is that it doesn't support all programs as well as running Windows with either Parallels or Bootcamp.