Not sure. You might be able to OC it to the moon, but then it may blow up a week later. Finding a happy medium in overclocking (not going too far) is essential. Considering the E2160 is only a dual core and the Q6600 being quad would make a hell of a difference. Even if you only OC'd it to 3Ghz. The larger L2 cache makes it soooo much faster.
For example,
the E2160 has 1Mb of L2 cache where the Q6600 has 8Mb
the E2160 runs on an 800Mhz FSB where the Q6600 uses 1066Mhz
Its all round a stronger component. This comes from personal opinion though, as I have a Q6600....:wink:
I managed 3.1Ghz with my MSI P31 Neo, so you would probably manage the same but slightly more stable.