[PolkaDot]

A few times recently after my computer shut downs improperly (from either a power loss or from a hard restart from freezing), it will start up with a black screen that says:
"Remove disks or other media. Press any key to restart."
If I click any key, it'll say:
"Reboot and Select proper Boot device or Insert Boot Media in selected Boot device and press a key."
If I click any key, it'll just go back to the first message.

I think this is because it is not seeing my primary HDD (Drive C). I go into bios and it only lists my secondary storage drive (Drive E) as well as the DVD drive. It's like it doesn't even see my primary HDD.

Any thoughts on what might be going on?
After fiddling around and not changing anything, it'll work after awhile. Not sure if there was anything I did besides giving it a chance to try a handful of times.

Any reason after a shut off, it wouldn't see my primarry HDD?
My computer is an ASUS running Windows 10.

 

[spunk.funk]

The drive may be failing. You didn't say, is your ASUS computer a laptop or a desktop?
If a Desktop, shut down and take the side cover off. Check the cabling on the Main HDD. Make sure the SATA Data and power plug are plugged in tight to the back of the drive and follow the SATA Data cable to the motherboard and make sure it is in tight there. You can also replace the SATA Data Cable. Choose a different power plug from the PSU.
Once in Windows, download Disk Genius, in my signature. Select your disk, and go up to the Toolbar to Disk then first select View SMART information. then View or Repair Bad Sectors. If all of the boxes are Blue then the drive is healthy, if any boxes are Amber or Red they are bad sectors, You can try to Repair, but the drive should be replaced.