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If the Systems Properties window indicates that the Hard disk drive is running in MS-DOS compatibility mode, attempt the below recommended steps.
Before following the below steps, if you are running a DDO (Disk Drive Overlay), which is a utility that installs and sets up a hard diskette drive using a floppy diskette, it is recommended that you contact the Hard Disk Drive manufacturer for possible updated drivers for the DDO or recommended steps.
1. Boot from a clean write protected boot diskette.
2. Once at A:\> type fdisk /mbr and press enter, this should return you to the A:\>
3. Type sys c: and press enter, once the system has been transferred, remove the diskette and reboot the computer.
4. Ensure a CD-ROM is installed in the computer, some computers may have a CD-ROM drivers loaded but may not have a CD-ROM installed.
5. From Windows click Start / Shutdown / Restart the computer in MS-DOS mode.
6. At the DOS prompt type cd\ and press enter to get to the C:\> prompt.
7. At C:\> type ren autoexec.bat autoexec.ch and press enter to rename the autoexec.bat temporarily.
8. Once this file has been renamed type ren config.sys config.ch and press enter to rename the config.sys.
9. Once each of these files have been renamed, reboot the computer to see if the issue has been resolved.
Windows 98 only users
1. On the Windows 98 CD, open the Tools\mtsutil folder
2. In this folder locate the noide.inf file.
3. Right click the file and choose install.
If the issue persists, it's a good possibility that either the hard diskette drive is bad/corrupted or Windows is corrupted. I would recommend that you first attempt to reinstall Windows. You can try a repair install. If this does not resolve the issue, I recommend that you fdisk, format and reinstall all the software on your computer.
http://www.computerhope.com/issues/ch000143.htm