Blue screen when game cd isn't in

Hi all-

I am having a problem where when I try to start this game (Combat Flight Simulator 2) and the CD isn't in, the computer flashes the all-too-familiar blue screen. The weird thing is that the screen only says "Please insert a disk into drive B". I don't have a drive B, and the CD drive I use for this is drive E. Anyway, after hitting a key, the floppy drive goes nuts and the screen is black except for a square of what was on the screen before where the mouse pointer was. The floppy drive will continue to do it's thing until I put a floppy in (strange, huh?). At this point it stops and the screen returns to normal. After a couple of seconds, it will say something to the effect of "Please insert the Combat Flight Simulator 2 CD", but if I try to launch again (this is from the Zone, but the problem will still occur when launching from it's shortcut) it will just hang until I cancel it.

Any ideas?

This is driving me nuts since every time I forget to put the CD in I am forced to restart before I can play and this computer is old so it takes forever.