Hi kandy_k_46804
Sorry it's taken so long to get to your question - I've been very busy. Did you have any luck yet in solving your problem?
If not, read on:
1) Check the plugs (with the computer powered off & the power cord unplugged). If your mouse and keyboard are the PS/2 type (that is, not USB) they could be plugged into the wrong connectors. If your connectors are color-coded, the mouse connectors should be green & the keyboard connectors colored purple. Once you are sure things are connected right (if you have a USB mouse and/or keyboard, try unplugging & then replugging them), go to step 2.
2) Try booting into Safe Mode. As soon as your computer is powering up, start tapping the F8 key on your keyboard. Choose Safe Mode from the menu.
3) If the mouse & keyboard run OK in Safe Mode -- try a run of your antivirus & antispyware programs, just to be sure.
4) Reboot, and see if the mouse and keyboard work in Normal Mode (booting normally).
5) If not, reboot into Safe Mode again. And try a System Restore, using a restore point from when the system was working OK. [Start/All Programs/Accessories/System Tools/System Restore]
6) Reboot, & test again. If still no luck, post that information here.
If you find that you have indeed suffered a serious malware infection, try the 5-Step Security Checklist here at Tech Support Forums to look at that in-depth --
http://www.techsupportforum.com/showthread.php?t=15968
I'd also recommend a run of Rootkit Revealer
http://www.sysinternals.com/Utilitie...tRevealer.html and Blacklight
http://www.f-secure.com/blacklight/try_blacklight.html
Best of luck!
. . . Gary
P.S. . . . and Welcome to the Tech Support Forums!