I would not loosen your ram timings until you "hit the wall" so to speak; which means there will come a time when you will squeeze all there is from your rig, at that time you can loosen timings and get another 10-15mhz on the FSB just for the heck of it
personally I dont overclock that agressively for myself, I would leave the ram timings at 4-4-4-12 at 2.1volts and then squeeze what you can get from the FSB you should be able to sqeeeze a guaranteed 300mhz after that things get tougher
even the 6000+ was hailed as the overclock gods cpu, yet 15% overclock needed water cooling to sustain
enjoy; just dont forget to run your stability checks (orthos or prime) as you go
increase your fsb 15mhz at first step then keep climbing by 10's afterwards
run orthos for one hour to check for each step stability
once you achieve your first failure of prime, then back off 15mhz on the FSB and run prime for 2 hours that will be your "working" overlock
sooooooo many overclockers think if you can boot into windows you are safe >>>> THAT IS A VERY MISGUIDED MISCONCEPTION
there is another crowd which thinks if you can game for two hours with crashing your overclock is a safe one >>>>>> WRONG
if you can pass a two or better yet three hour cpu stress test, then you are SAFE
some moderate overclock steps will not have any negative impact on the life of a system; more agressive steps will
only you can tell how much risk you are willing to accept
I would increase your cpu voltage to 1.45 volts but not more >>>> there are some that run 1.55 volts but thats too hot for this ole fart!
most of all >>>>> enjoy the challenge
