Hi griffy and welcome to TSF
Sorry for the delay in getting to you, the forum has been really busy lately and all our helpers are volunteers.
You are quite heavily infected so cleaning will take several posts. Please continue until you are told you are clear. Please also follow instructions in the exact order stated.
I see a large number of infected crack files have been disinfected by Panda

Not only are cracks illegal but they are most likely the cause of your current problems.
Empty the contents of the following
Folders (DO NOT delete the folder)
C:\Documents and Settings\LocalService\Cookies
C:\Documents and Settings\User\Cookies
----------------------------
Download
Combofix from any of the links below, and save it to your desktop.
Link 1
Link 2
Link 3
**Note: It is important that it is saved directly to your desktop**
--------------------------------------------------------------------
1. Close any open browsers.
2. Close/disable all anti virus and anti malware programs so they do not interfere with the running of ComboFix.
If your not sure how to disable them then double-check against the list found
>>>HERE<<< This list is not all inclusive, if your programs are not listed and you are unsure then please ask before continuing.
--------------------------------------------------------------------
Double click on
combofix.exe & follow the prompts.
- When finished, it will produce a report for you.
- Please post the "C:\ComboFix.txt" along with a new HijackThis log for further review.
Note:
Do not mouseclick combofix's window while it's running. That may cause it to stall